Healthcare WHAT MAKES STERILE FILTRATION UNIQUE?


WHAT MAKES STERILE FILTRATION UNIQUE?

Meaning of sterile filtration:

Sterilizing filtration is presently a known solution in pharmaceutical manufacturing and is employed in order to cure microbial contamination from negatively impacting drug quality and, more importantly, to guarantee patient safety. In the simplest words, sterilizing filtration is the procedure of detaching microorganisms (not the viruses) from a fluid stream without adversely affecting product quality. Sterile filtration is usually employed moreover for microbial removal and plays an important role in assuring final product sterility. To select the right procedure for sterile filtration it's very necessary to apply some strategies for ensuring safety for the patients. One can employ the integrity test for assuring the performance of filtration, also it's necessary to tale right filtration process, minimize the risk of contamination through the quality checks, etc.

Filtration Sterilization Mechanism in Action:

Filters operate by physically trapping particles larger than the pore size and electrostatically attracting smaller particles to the filters to hold them. Other variables, in addition to porosity, influence filtration performance, including:

  • the filter's electric charge
  • the species carry an electric charge.
  • the essence of the fluid that needs to be filtered

Filtration of liquids is achieved by either pulling the solution through a cellulose acetate or cellulose nitrate membrane with a vacuum (i.e., applying negative pressure in the filter paper) or pushing the solution through the filter paper by applying positive pressure above the fluid. High-efficiency particulate air (HEPA) filters are used to filter the air in isolation rooms, operating rooms, and biological safety cabinets to eliminate species greater than 0.3 m.

What is the Process of Sterile Filtration?

Filtration is done with membranous filters, which have tiny pores that allow liquid to pass through but prevent larger particles like bacteria from passing through. As a result, the smaller the pore, the better the filter's chances of preventing more items from passing through it. If the pores of a filter designed to extract a microbe, a microscopic organism, are small enough, they should be able to keep all living things out.

Sterile Filtration's Benefits:

1. Cheap, with the exception of those with the smallest pore sizes.

2. Filters are not easily clogged.

3. Since filters do not use heat, they are suitable for heat-sensitive liquids.

4. They can process significant amounts of fluid in a reasonable amount of time.

Final Thoughts: 

In laboratories, filtration is an interesting sterilization process. It's the only tool that separates people rather than killing them. Filtration equipment and filters may be purchased as pre-sterilized disposable units in sealed packaging, or they can be sterilized by the customer, usually by autoclaving at a temperature that does not harm the delicate filter membranes. The sterile filtration market is expected to grow significantly during the forecast period, owing to increased research and development spending by pharmaceutical and other companies, as well as a growing number of biotechnology and pharmaceutical companies to drive the market growth.

Sterile Filtration Market: 7.9% CAGR

Projected Revenue: 8.84 billion from 2021 to 2027

For deeper dive check the full report here: https://whipsmartmi.com/Report/Sterile-Filtration-Market

Published Date : March-2021